The professor was reported to have died at the Senate chambers of the institution on Friday at about 2pm, shortly after reading his manifesto to about 300 delegates. He was said to have been in his 50s.
Professor Isika became a professor six months ago.
A medical consultant at the University of Calabar Teaching Hospital told PUNCH on Sunday that the professor might have died of cardiac-related ailment.
According to him, "Isika had just finished his electioneering campaign and in less than five minutes after addressing the senate, he slumped and died in his seat.
The medical doctors gave him first aid before rushing him to the hospital, but before they got there, he was already dead. Part of the indication was that he was hypertensive".
Mr. Eyo Effiong, the Public Relations officer of UNICAL confirmed the incident saying "it was a tragedy that the man should die that way after attaining such height in his educational pursuit".